Q5 .What scale of synthesis does BOL offer?

Scale of synthesis refers to the amount of starting CPG (controlled-pore glass) which is used to initiate the Oligomers synthesis, NOT the amount of final compound synthesized. As an example, a 20 mer Oligomer which synthesized at a 250 nanomole scale of synthesis will produce approximately 100 nanomoles. The losses occur during synthesis, post-synthetic processing, transfer of material, and quality control. BOL can synthesize from 25 nmole upto 200 Ámole synthesis. 25 nmole = 15-60 bases, 100 nmole = 10-90 bases, 250 nmole, 1 Ámole = 10-100 bases, 10 Ámole or more =5-50 base


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